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The CDC recommends that children with moderate to severe malnutrition or stunting (low height-for-age) should not be treated for malaria. These children are more likely to develop more serious health problems, including adverse outcomes after treatment. Also, severe illness and even death may occur with the use of artemisinin-based combinations (when associated with inappropiate dosing of co-intermediates, such as piperaquine) in children with uncomplicated malaria. Malaria vaccination has been recommended by WHO for children in areas where the risk of malaria is very high, and where malaria infection is endemic. The vaccine has been shown to be highly effective against severe malaria, and to prevent malaria in young infants. The World Health Organization (WHO) recommends that children with moderate to severe malnutrition or stunting (low height-for-age) should not be treated for malaria. These children are more likely to develop more serious health problems, including adverse outcomes after treatment. Also, severe illness and even death may occur with the use of artemisinin-based combinations (when associated with inappropiate dosing of co-intermediates, such as piperaquine) in children with uncomplicated malaria.People at high risk include:
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